Introduction: Kidneys are the most vital organs in the human body. Kidneys perform vital functions like excretion of waste products, maintenance of water balance, thus maintaining the homeostasis. In addition kidneys perform many other functions such as role in homeostasis, production of erythrocyte, endocrine functions, and regulation of blood calcium level. Methods: A pre experimental research approach with one group pre-test design which includes manipulation, without control and randomization. The study includes 30 patients who are selected as a sample by nonprobability convenient sampling technique. Result: We enrolled 30 samples. Thus we concluded that the overall pre-test knowledge of experimental group is having the same level of knowledge, the main value of experimental group was 4.5 (30%). The overall post-test knowledge means group scored in mean value of 10.4 (69.3%). Thus the patients in dialysis unit among the experimental group have scored high in post-test. Hence the research study was preferred to be highly significant. Discussion: The findings of this study revealed that knowledge of the patients having more knowledge regarding kidney transplantation on ESRD after giving the structured teaching programme. Thus we concluded that the selected sample need on-going classes periodically regarding kidney transplantation on ESRD.

Keywords : Effectiveness, ESRD, Knowledge, Kidney Transplantation.