To study and compare Postoperative analgesia
with Plain Ropivacaine 0.25% and Plain Ropivacaine
0.25% with Clonidine 1µg/kg in pediatric patients.
Aim:to determine the efficacy of clonidine as an
adjuvant to caudal anaesthesia with ropivacaine
Settings and Design:
Methods and Material: In single blinded study, 80 ASA
I/II patients of 2-9 yr age undergoing infraumbilical
surgery were studied. 40 patients allocated to RC group
were given with 0.25% Ropivacaine with 1µ/kg of
Clonidine(0.5ml/kg) caudally and compared with rest 40
in R group which were given with 0.25% Plain
Ropivacaine (0.5ml/kg). Haemodynamic parameters like
heart rate blood pressure studied intraoperatively, Pain
score with FLACC (Face Legs Activity Cry
Consolability) scoring and sedation score were observed
postoperatively at 1, 2, 3, 4, 8, 12, 24hrs. Rescue
analgesia was provided by Diclofenac suppository 1
mg/kg.
Statistical analysis used: Unpaired t-test and ANOVA
Results: Significantly prolonged duration of
postoperative analgesia was observed in RC group than
in R group (Significant difference in pain score was
observed at hrs postoperatively, with no significant
difference in intraoperative Heart rate, blood pressure
and postoperative sedation score and adverse effects in
both groups.
Conclusion: The combination of Ropivacaine with
Clonidine in caudal anesthesia in pediatric patients
significantly improves postoperative analgesia without
causing significant haemodynamic instability,
postoperative sedation and residual motor blockade.
Keywords : Ropivacaine, Clonidine, Caudal Analgesia.