The patient safety culture of the health personnel is linked to attitudes and beliefs to avoid any harm that may be caused during the stages of health care. The objective of the research is to determine the level of patient safety culture among the nursing personnel of the Homero Castanier Crespo Hospital. Methodology: A non-experimental, descriptivecorrelational and prospective cross-sectional design study was carried out, with a quantitative approach, with a study population of 161 nurses and nursing assistants; a survey was used to obtain sociodemographic data, and the instrument used to determine the patient safety culture was the Medical Office Survey on Patient safety -MOSPS Questionnaire. Results: According to age, the most prevalent age range was 30- 39 years with 51.6% (83); the most prevalent sex was female with 94.4% (152); in relation to the number of years working in the hospital, 34% (56) worked for more than 10 years; according to the type of contract, 59.0% (95) worked with a permanent contract. With regard to the patient safety culture, the following were identified as strengths: teamwork and respectful treatment; carrying out activities aimed at improving patient safety, preventive measures, evaluation of effectiveness after introducing changes to improve safety; the general appreciation that the management is interested in patient safety and that there is communication with the nursing staff. However, the frequency of reported events prevalence is low; in the nursing staff perception of the degree of Patient Safety is very good. Conclusion: The determinants of safety culture depend on interprofessional and administrative relations. If patient safety is promoted, the safety of the healthcare personnel is promoted.

Keywords : Patient Safety, Health Care, Nursing Care.