This article conducts unique research on the design of puzzle games for the prevention and intervention of the elderly with Alzheimer's disease. This article combines the investigation and research on the elderly with Alzheimer's disease. It also summarizes the physiology, mental state, pathogenic factors and living habits of the elderly through the research method. In addition, it considers the design principles of ease of use, safety, and interest in combination with information technology. Finally, a game with a rehabilitation function that provides mental exercise training was designed. These games will be tested in the future. The extended physical products of related training games will be suitable for home or community activity centres.

Keywords : The elderly, Alzheimer's disease, rehabilitation, Serious Games