Diclofenac, a phenylacetic acid derivative and NSAID with the chemical formula of C14H11Cl2NO2. It shows high effectiveness in order to treat pain and physical disability in rheumatic diseases. There are multiple kinds of adverse effects related to this drug, and it is necessary to know the drug before administration, including its adverse effect. This mini-review is focused on its introduction, efficacy after oral administration, and adverse effect

Keywords : Diclofenac, NSAID, Oral Administration, Adverse Effect