As a part of normal life, the Reactive Oxygen Species, Oxygen-derived radicals, free radicals are generated constantly and also when body exposed to few factors like strong chemicals and UV rays. In this study, the DNA protection nature of Polyphenols from Curry leaves against UV rays was studied. The above study was done using submarine gel electrophoresis in which, the DNA was damaged using UV rays of selected wavelength. A maximum of 15μg dosage of polyphenols enriched extract was taken to prevent the DNA fragmentation and the protection level was compared with positive control Ascorbic acid (400μM). It was observed that, the Polyphenols of Curry leaves and standard antioxidant like Ascorbic provides a protection of 69% and 63% respectively, which provides an impression that, polyphenols of Curry leaves provides protection to DNA

Keywords : Curry leaves extract, DNA damage, DNA protectant, Cytoxocity, UV rays, Polyphenols, Non-toxic