Dyslipidemia is a lipid metabolism disorder in the body is a risk factor for cardiovascular disease which causes 17.9 million deaths each year or about 31% of total deaths in the world. This study aims to assess the effect of medication adherence on the lipid profile of dyslipidemic patients in pharmacies.This study was conducted in a cross-sectional manner by tracking the patient's condition, patient medication records, and assessing adherence based on the MMAS-8 questionnaire. The study involved 45 respondents who became patients at the pharmacy and then assessed compliance and the results of their therapy. The data were analyzed using the Spearman statistical test. The results showed that there was a strong correlation (p <0.05) between adherence and total cholesterol (r = - 0.717); LDL (r = -0.541); and TG (r = -0.327).However, adherence did not have a significant relationship with HDL levels (p> 0.05) with a correlation value of r = 0.121. The improvement in the lipid profile was indicated by a decrease in total cholesterol, LDL, and triglyceride levels towards normal and increased HDL levels. The results of the study concluded that patient adherence in taking medication had an effect on improving the lipid profile of dyslipidemic patients by reducing levels of Ktotal, LDL, and TG but did not significantly influence the increase in K-HDL levels.

Keywords : Adherence; Lipid Profile; Dyslipidemia; Pharmacy Services.