Basic immunization is one of the prevention programs of infectious diseases for children. Objective: This study is to identify the effectiveness of the Android-based KIE on parents' compliance in giving basic immunizations in infants before the age of 1 year in the Covid -19 pandemic period. Method: quasy experimental pre-post test with control group. Samples amounted to 40 people with systematic random sampling. The instrument used by the questionnaire in the form of google form about parents' compliance regarding the basic immunization distributed through the WhatsApp application. Results and Discussion: The results of the T dependent test are obtained there is an influence of the Androidbased KIE on parental compliance in the provision of basic immunizations in infants before the age of 1 year in the Covid -19 pandemic period (p = 0.003). Conclusion: Kie-based Android is effective against parents' compliance in giving basic immunizations in infants before the age of 1 year in the time of the Covid -19 pandemic. Suggestion: It is expected that health workers can provide information and education communication (KIE) as a promotive effort especially regarding the implementation of basic immunizations in intensive and structured pandemic times and considering educative animated media and animated videos so that they can be more effective and efficient.