The purpose of this study was to determine, analyze and assess which sectors are the leading sectors in the four regions in Tana Luwu with the Location Qoutient (LQ) analysis approach. It was concluded that the economic potential of each region is different. East Luwu Regency has a base sector in mining and quarrying. North Luwu Regency has base sectors in agriculture, forestry and fisheries; electricity and gas procurement; government administration, defense and social security; and educational services. Palopo City has a base sector in electricity and gas procurement; water supply, waste management, waste and recycling; construction; wholesale and retail trade; car and motorcycle repair; transportation and warehousing; financial services; real estate; government administration, defense and social security; and health services and activities. And Luwu District has base sectors in Agriculture, Forestry and Fisheries; electricity and gas procurement; real estate;Government Administration, Defense and Social Security; health services and social activities.

Keywords : Leading Sector, Gross Regional Domestic Product, Location Quotient (LQ), Tana Luwu