The interplay between free radicals and antioxidant has gained a greater research momentum owing to their implication in the pathophysiology of several pathologies. Even though these chemical species have high reactivity and cause damage, they are still essential components of certain biological processes that occur at molecular level including immune function. The functions of such chemical species in immunotoxicity; the beneficial and detrimental effects in immune response remain the central focus of this review. Nature has put in place a system for defense which if compromised will increase the susceptibility of the body to disease-causing agents. The mechanisms of selected free radicals that mediate immune function in a myriad of medical conditions is the subtheme in this short review.

Keywords : Oxidative Stress, Immunotoxicity, Immune Response