The study investigated Perceived Determinants of Brain Drain among Mental Health Professionals in Specialist Health Care Facilities in Benin. A cross sectional predictive research design was adopted using two facilities: Federal Neuro-Psychiatric Hospital Benin and the Department of Psychiatric and Mental Health, University of Benin Teaching Hospital, Benin City. Population for the study consisted of 299 respondents drawn from the facilities (277 from Federal Neuro-psychiatric Hospital Benin and 72 from University of Benin Teaching Hospital). Purposive sampling technique was employed. Sample size was allinclusive. Target population were mental health care professionals in specialist health care facilities in Benin City. The instrument for data collection was the Brain Drain Prediction Scale, developed by the researcher. The instrument was tested for validity and reliability. The ethical approval was also obtained. Data were collected by means of questionnaire. Percentages, frequencies and Chi-Square statistics were used in analyzing the data. Result revealed that there were significant relationship

Keywords : Brain-drain, Determinants, Health Care Professionals and Specialists Facilities.