Standard precaution as the main precaution is applied routinely in hospital care. So it is important to know how the application of standard precautions carried out by nurses as health workers who spend more time interacting with patients during service and have a large influence on the high incidence of HAIs. This study uses phenomenological design with the aim of obtaining an overview of nurses’ experience in applying standard precautions in anticipation of HAIs. The Participants consist of ten participants. Data was collected through the Focus Group Discussion method and in-depth interview. Data analyzed by the Collaizi method. The results of this study found 7 themes : 1) Nurses know the concept of standard precautions in anticipation of HAIs; 2) The nurse’s hand hygiene behavior is still not consistent in every action; 3) Negligence of nurses in the use of PPE; 4) Management’s efforts to respond problems in implementing standard precautions have not been optimal; 5) Motivation of nurses in applying standard precautions; 6) Constraints of perception and facilities in the application of standard precautions; 7) Nurses’ expectations in applying standard precautions. It is expected that the hospital management can facilitate nurses in infection prevention and control equipments and improve nurse quality with equitable basic prevention and control training.

Keywords : HAIs, Standard precautions, Nurses.