The impending coronavirus disease 2019 (Covid-19), and the risk of its worldwide pandemic development requires urgent effective therapeutic procedures, being it orphan of a specific vaccine predictably for the next 24 months or more. Attempts to treat the infection with some chemotherapies borrowed by other antiviral registered schedules or with other adopted off label drugs are on the way, but our concern is to run against the time adding if possible a further safe, effective sustainable treatment available to the greatest number of people anxiously claiming for prevention or disease control. We focused on the challenge of an impressive bacterial quick and safe antiviral activity, incidentally observed on advanced metastatic cancer injected on a compassionate spontaneous basis with dead bacteria into the tumor masses (years 1975-79). The present paper describes the details of our experience namely with Corynebacterium parvum which displayed the best effective and safe viral symptoms remission in comparison with BCG and one autochthonous wild strain of Streptococcus faecium. We successfully followed up with this procedure occasionally in the more recent years in some cases voluntarily requiring vaccination after detailed informed consent acceptance, to relieve their aggressive cumbersome viral infections. The take home message of this report is to take in account not only the excellent new tailored Gene targeting therapies, but, especially in emergency, to do not absolutely forget the old ones!!!