Temporomandibular joint is a giglymoarthroidal joint which is composed of a synovial cavity, capsule and an articular cartilage. It’s a very sensitive joint that it can easily undergo degenerative changes which in turn compromise the quality of life of the patients. There are several invasive and non-invasive treatments for the rehabilitation of disc degeneration. With regenerative medicine, the treatment planning can be done efficiently utilising minimally invasive and noninvasive methods which can improve ease and comfort of the patient. Tissue engineered implants, prolotherapy, intra articular injections of growth factors are novel approaches in establishing a better treatment outcome.

Keywords : Temporomandibular joint, regenerative medicine, tissue engineering, implants, Prolotherapy, Intra articular injections.