 Introduction: This study has been conducted to assess the prevalence and factors associated with musculoskeletal morbidity amongst the workers involved in the tailoring occupation  Aim &Objectives: 1.To assess the prevalence of musculoskeletal morbidity amongst tailor in a rural area of Tamil Nadu. 2.To assess their ergonomical factors in the workplace.  Materials and Methods: A Cross sectional study was conducted in a rural area of Tamil Nadu over a period of 3 months from March to May 2019. The sampling frame comprised of tailors in a rural area of TamilNadu. A total of 50 subjects who were willing to participate in the study were interviewed (p=66%). The sampling method was simple random sampling and the data collection tool was a questionnaire and the data collection technique was the interview method. Data entered in excel sheet and exported to SPSS for windows , version 16.0 software for analysis  Results: In this study, 50 questionnaires were returned by the individuals involved in the tailoring occupation in Chennai. The prevalence of the various musculoskeletal morbidity risk factors in tailors were found to be significant. Working hours has been found to cause trouble in the last 12 months in 26% individuals who work more than 8-10 hours per day, chair without backrest has caused trouble which hasn't allowed a person to do work in the past 12 months in 28% individuals, and unsatisfactory workstation ergonomics has caused trouble in the past 12 months in 34% individuals, apart from others. Musculoskeletal morbidites were found in individuals 52% , and is found to have a significant relationship with being a tailor.  Conclusion: To recommend suitable ergonomical alternatives and reduce associated musculoskeletal morbidities.