The case report discusses case of 32 years female with a large pedunculated villous adenoma which was mimicking intussusception of duodenum. Almost all such lesions can be visualized endoscopically, but, large lesions which cause luminal obstruction pose a difficulty.

Keywords : Villous Adenoma, Intussusception, Esophagogastroduodenoscopy, Lateral Duodenotomy.