Periodontal regeneration is defined as the reproduction or reconstitution of a lost or injured part to restore the architecture and function of the periodontium. The goal of periodontal therapy is to regenerate the destructed periodontal tissue by periodontitis. Efforts to achieve periodontal regeneration in intrabony defect has been achieved using various types of bone grafts. Platelet Rich Fibrin is autologous preparation which is considered as second-generation platelet concentrate consisting of viable platelet releasing different types of growth factors. It is found to be clinically effective and economical for use. This case report presents the clinical and radiographical effectiveness of autologous Platelet rich Fibrin in treatment of intrabony defect.

Keywords : Intrabony Defect, PRF, Regeneration.