The scientific learning that was launched in the 2013 curriculum is a form of the effort of Indonesian government to improve the quality of human resources. Scientific learning process is not only just transferring knowledge and skills but also buildingHigher Order Thinking Skills (HOTS). Study is aimed to develop a guided inquiry based module and to see the validity and practicality. The kind of research study conducted is Research and Development (R & D) by using the model of Plomp Development which consist 3 phases, they are (1) Preliminary research, (2) Prototyping stage, and (3) Assessment phase. The validity test was carried out by 4 chemistry lecturers of State University of Padang, 1 chemistry teacher at SMAN 1 Painan and 1 chemistry teacher at SMAN 3 Painan. The practicality test was carried out by 2 teachers of chemistry at SMAN 1 Painan and 2 teachers of chemistryat SMAN 3 Painan and 36 students from SMAN 1 Painan and 24 students from SMAN 3 Painan. The results of the research analyzed by the Cohen Kappa formula show that the Guided Inquiry Based Module is valid for use as a learning medium, as evidenced by the validation result data limitations of content aspects, constructions, language and graphic component, respectively 0.90, 0.90, 0.88 and 0.87 including in the very high category. The practical aspects of the Small Group are reviewed based on the criteria of convenience, time efficiency, and benefits respectively getting 0.86, 0.77, 0.82 and the practicality of the Field Test respectively 0.83, 0.83, 0.86 in the very high category. While the results of the practicality of the teachers were respectively 0.89, 0.86, 0.98 in the very high category.

Keywords : Validity, Practicality, Module, Guided Inquiry, HOTS.